Goodwin scored 16 of his points in the first half when Saint Louis took a 35-23 lead. Roby, with just two points in the first half, opened the second with a pair of 3-pointers and added a 3-pointer and a layup in an 8-0 burst for a 23-point lead with 11:38 to go.
Denzel Mahoney, who came in first in the Ohio Valley Conference at 19.2 points per game, finished with 12 on 3-of-9 shooting for the Redhawks (6-7), who shot just 32 percent.
The Billikens (7-6) finished their nonconference schedule with a winning record for the first time since 2014-15.
Andy Enfield gets another talented big man for USC's 2019 class.
Kansas fired athletic director Sheahon Zenger on Monday, with school chancellor Douglas Girod also noting football coach David Beaty continued preparation for the 2018 season.
Matt Woodley knows life as an assistant coach means often uprooting his family. After one season at Pitt, he took a job at Drake to seek stability for his daughter Molly, who suffers from life-threatening seizures.