JaShaun Smith hit a 3 to reduce Longwood's deficit to 25-15 with 6:49 before halftime, but Cortez Mitchell made a layup and Fleming buried another 3 for a 15-point lead. Fleming's last 3 of the half put the Buccaneers up 42-23 at the break.
Charleston Southern extended its lead to 61-30 with a 19-7 run after intermission with Keeling scoring eight and Cortez Mitchell adding seven. Mitchell finished with 13 points and McConico scored 10.
Smith led Longwood (3-11) with 15 points.
Jim Calhoun, who has a career record of 873-380 and led UConn to three national titles before retiring in 2012, has been hired as coach at Saint Joseph.
Pac-12 commissioner Larry Scott believes a tentative ruling making show-cause orders illegal in California would threaten NCAA membership for state schools.
Guard James Bouknight, ranked 87th in the ESPN 100, is the first player from the Class of 2019 to commit to UConn and first-year coach Dan Hurley.