Striving to tie the major league record of homering in eight consecutive games, Morales went 0-for-3 with a walk and did not hit the ball out of the infield. In his final chance, the Toronto slugger swung through a slider from Paul Fry to strike out in the eighth inning.
Though he failed to match the mark shared by Dale Long, Don Mattingly and Ken Griffey Jr., Morales owns the big league record for successive games with a home run by a switch-hitter. He also owns the franchise record for consecutive games with a long ball.
Facing Baltimore rookie David Hess, against whom he homered last week, Morales struck out in the first inning, grounded out in the fourth and drew a four-pitch walk in the sixth.
Hess (3-8) tossed six innings of four-hit ball to earn his first win since May 25. He was 0-7 in his previous 12 starts, though he did pitch very well against Toronto his last time out.
The game was scoreless until the Orioles broke through in the sixth against Sam Gaviglio (3-7). After Chris Davis drove in a run by hitting into a fielder's choice with the bases loaded, Trey Mancini hit a three-run homer to send Baltimore on its way to its first win since Aug. 18.
Mancini added a two-run double in the seventh and scored on a single by Tim Beckham. The five RBIs for Mancini matched his career high.
The Orioles improved to 2-12 against Toronto.
Morales endured an 0-for-29 skid in May and had only 14 homers on Aug. 14 before launching his improbable streak.
"It's been a surprise. I didn't see it coming," Toronto manager John Gibbons said. "What's made it more incredible is the overly extended slump at the start of the season."
When Morales is on a roll, even pitches out of the strike zone can end up soaring over the outfield wall.
Asked how his staff could keep Morales from tying the record, Orioles manager Buck Showalter said, "It's so easy to sit there and go, 'Listen, just don't throw him anything.' It's hard to pitch around him, quite frankly."
OLDIE BUT GOODIE
Toronto reliever Murphy Smith became the oldest Blue Jay to make his major league debut, at 31 years and 2 days. He has pitched in 277 minor league games.
Blue Jays: 3B Josh Donaldson (left calf tightness) will start a rehab assignment Tuesday at Class A Dunedin. He has been sidelined since May 29. ... INF Brandon Drury (broken left hand) had imaging done and is scheduled for another MRI later in the week, Gibbons said. ... INF Yangervis Solarte (right oblique strain) has started strengthening exercises. ... RHP Marcus Stroman (middle finger) has started catching and throwing progressions.
Orioles: Rookie CF Cedric Mullins returned after missing Sunday night's game with a sore hip.
Blue Jays: LHP Thomas Pannone (1-0, 1.59 ERA) seeks his second big league victory in his second career start Tuesday night. He blanked the Orioles over seven innings last Wednesday in his starting debut.
Orioles: Showalter said he would announce his Tuesday starter after the game.
More AP MLB: https://apnews.com/tag/MLB and https://twitter.com/AP-Sports
Cards' Yadier Molina takes exception to quips by Cubs' Kris Bryant
Cardinals catcher Yadier Molina took exception to quips about St. Louis by Cubs star Kris Bryant and Ryan Dempster, saying only "stupid players and losers" make fun of other cities.
Buster's Buzz: Red Sox repeat? Four question marks facing the champs
From health to hangovers, Boston still must find a few answers in its quest for a second straight ring.
Yankees sign reliever who criticized Babe Ruth
Mike Golic finds it comical that the Yankees signed reliever Adam Ottavino who previously stated he would "strike out Babe Ruth every time."
Kris Bryant: 'Not good' that stars Bryce Harper, Manny Machado remain unsigned
Kris Bryant and Evan Longoria expressed frustration that several free agents, including stars Bryce Harper and Manny Machado, are still looking for jobs as February nears.
Red Sox manager Alex Cora may reconsider decision to visit White House
Red Sox manager Alex Cora, a Puerto Rico native who has been outspoken about its need for hurricane relief, indicated on Thursday that he may skip the World Series celebration at the White House over President Trump's policies toward the island.
Angels reach one-year deal with Cody Allen to be closer next season
The Los Angeles Angels have reached an agreement with relief pitcher Cody Allen on a one-year deal to be their closer next season, league sources told ESPN.