PHILADELPHIA -- Stephen Strasburg made all the necessary adjustments.
Strasburg (7-7) gave up two runs and five hits, striking out five to rebound from a rough start against Philadelphia last week in his return from the disabled list.
"So many little things hitters try to pick, so you always have to look at the tendencies," Strasburg said. "It was progress."
The Phillies fell 3 1/2 games behind first-place Atlanta in the NL East after losing the opener for the seventh straight series. They're 6-12 since Aug. 8 and have dropped five games in the standings during that span.
Zach Eflin (9-5) allowed five runs -- three earned -- and eight hits in 5 1/3 innings. His throwing error in the fourth cost him.
The Nationals had the bases loaded with one out that inning when Strasburg put a bunt down. Eflin picked it up barehanded and his underhand toss to the plate sailed high for an error, allowing the go-ahead run to score.
Adam Eaton followed with a slow roller to the same spot and Eflin made the exact same play and got the out at home.
"We gave them additional outs and you can't do that against this team," Phillies manager Gabe Kapler said.
Eaton greeted reliever Luis Avilan with an RBI double in the sixth to make it 5-2.
Hoskins crushed Ryan Madson's first pitch in the eighth for his 27th homer.
Justin Miller tossed a perfect ninth for his first save in his first try in his 39th appearance.
"He comes in and brings so much energy on the mound," Strasburg said. "The hard work pays off."
Wieters led off the second with his sixth homer to make it 2-0. He said he was using a new bat after realizing the one he used the past few games was cracked.
Strasburg allowed five runs and seven hits over four innings in Washington's 8-7 win against Philadelphia last Wednesday.
"He was able to locate his fastball, throw a high fastball, and made corrections since the last start," Wieters said.
BOOING THE BUFFALO
Wilson Ramos was thrown out trying to go first to third on Cabrera's single to right and heard boos from Phillies fans even though he is playing hurt. Ramos recently returned from a hamstring injury and isn't healthy enough to do more than jog, but he's Philadelphia's cleanup hitter and wants to be in the lineup to help the team chase a playoff spot.
"He's playing through a lot," Kapler said. "He's a guy who gives everything he has and he showed a lot of toughness."
NEW MAN ON TOP
Quinn led off for the first time and Hernandez batted third for just the third time in 641 career games.
Nationals: RHP Kelvin Herrera was placed on the 10-day disabled list with a torn Lisfranc ligament in his left foot. Madson took his spot after he was reinstated from the DL.
Phillies: LHP Austin Davis (lower back tightness) began a rehab assignment at Triple-A Lehigh Valley. ... INF Pedro Florimon (broken right foot) is continuing his rehab in Triple-A. ... RHP Jerad Eickhoff (lat strain, finger) is expected to join the team when rosters expand Saturday.
RHP Aaron Nola (15-3, 2.13 ERA) and RHP Max Scherzer (16-6, 2.13) face each other for the second straight outing when the Phillies and Nationals meet Tuesday night. Nola tossed eight innings in Philadelphia's 2-0 win at Washington last Thursday.
More AP MLB: https://apnews.com/tag/MLB and https://twitter.com/AP-Sports
Veteran catcher Jeff Mathis agrees to two-year deal with Rangers
Jeff Mathis, one of the top defensive catchers in the majors, has agreed to a two-year deal with the Rangers, according to The Athletic.
Yelich: 'Unbelievable feeling' being named NL MVP
Christian Yelich joins SportsCenter after being named the National League MVP and receiving 29 of 30 first-place votes.
Newly crowned MVP Mookie Betts staking a claim as MLB's best player
Winning baseball's biggest award adds an exclamation point: There might be nothing that Boston's right-field star can't do on the diamond.
Yankees GM: Hustling 'always a prerequisite,' but won't discuss Manny Machado
While saying that hustling "is always a prerequisite" when signing players, Yankees GM Brian Cashman doesn't want any part of a debate about free agent Manny Machado
Brewers' Christian Yelich beats out Nolan Arenado, Javier Baez for NL MVP award
Brewers slugger Christian Yelich topped fellow finalists Nolan Arenado of the Rockies and Javier Baez of the Cubs for the National League MVP award Thursday.
Mookie Betts beats Mike Trout, Jose Ramirez to win American League MVP
Mookie Betts couldn't draw up a dream season much more perfect than this: a batting title, a 30/30 campaign, a World Series championship and now the American League MVP award.