Pass injured his toe in the season opener against Notre Dame, but finished the game and started the following week against Eastern Kentucky. But he re-aggravated the injury and has missed the last four games. Louisville said Pass will have surgery on Wednesday.
Last week against Wake Forest, Conley went 12-of-18 for 196 yards, two touchdowns and an interception in a 62-59 win.
Satterfield said during his news conference Monday he was not sure whether Cunningham or Conley would start against No. 3 Clemson on Saturday.
"I'll say what I've always said, that whoever's the healthiest and gives us the best chance, that's who we'll play," Satterfield said. "Both of those guys have played good. We've moved the football, had some good plays, taken care of the ball for the most part. Both can run, and we saw that with Evan the last run he had to score. We'll play the guy who's the healthiest. That's probably been the biggest question. I hate injuries, but that's part of the game. Whoever's the most healthiest, that's who will play."