The France left-back was charged on Aug. 26 with alleged attacks on three different women between October 2020 and August 2021 and was denied bail for a second time at the start of last month.
Mendy has been suspended by City, pending an investigation.
A statement issued by City following Mendy's arrest read: "Manchester City can confirm that following his being charged by police today, Benjamin Mendy has been suspended pending an investigation.
"The matter is subject to a legal process and the club is therefore unable to make further comment until that process is complete."
A second man, aged 40, was arrested on suspicion of rape as part of the police investigation into the allegations but was released on bail, police said.
Mendy joined City from Monaco in 2017 and has made 75 appearances for the club. After starting the 1-0 defeat to Tottenham Hotspur on the opening weekend of the season, he was an unused substitute for the 5-0 win over Norwich City on Aug. 21.