Santos, No. 9 in ESPN's divisional rankings, will be aiming to work his way back into title contention with a win over a rising prospect in Hill. Santos' last fight ended in a unanimous decision loss to Magomed Ankalaev. Meanwhile, Hill, who is unranked by ESPN, is quickly making a name for himself in the UFC. He enters the bout on a two-fight win streak after first-round finishes against Jimmy Crute and Johnny Walker.
The live finales of Season 30 of The Ultimate Fighter will also be on the card. Women's flyweights Brogan Walker and Juliana Miller and heavyweights Zac Pauga and Mohammed Usman will fight, with UFC contracts on the line for both winners.
Brett Okamoto touched base with an MMA coaching veteran to get his perspective on the matchup in the main event and how things could play out inside the Octagon. ESPN's betting experts Ian Parker and Reed Kuhn added their insights and analysis for everything from the main event to some intriguing bets they like lower down the card.