The main card at the UFC Apex will be on ESPN and ESPN+ at 10 p.m. ET. The prelims will be on ESPN+ at 7 p.m.
Barboza (22-9), a former lightweight, has won his past two fights. That came after he had lost his 145-pound debut in May 2020, giving him five losses in six bouts.
Chikadze (13-2) has won eight in a row, including all six of his UFC appearances.
Saturday's event also features finals of Season 29 of The Ultimate Fighter reality TV show. At middleweight, Bryan Battle faces Gilbert Urbina, and the bantamweight final pits Ricky Turcios against Brady Hiestand.
How to watch the fights
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All of the fights, prelims included, are on ESPN+. Get it here.
There's also FightCenter, which offers live updates for every UFC card.
Saturday's fight card
ESPN/ESPN+, 10 p.m. ET
Men's featherweight: Edson Barboza vs. Giga Chikadze
Middleweight (TUF final): Bryan Battle vs. Gilbert Urbina
Men's bantamweight (TUF final): Ricky Turcios vs. Brady Hiestand
Welterweight: Kevin Lee vs. Daniel Rodriguez
Middleweight: Andre Petroski vs. Michael Gilmore
Middleweight: Makhmud Muradov vs. Gerald Meerschaert
ESPN+, 7 p.m. ET
Middleweight: Alessio Di Chirico vs. Abdul Razak Alhassan
Middleweight: Sam Alvey vs. Wellington Turman
Light heavyweight: Dustin Jacoby vs. Darren Stewart
Women's flyweight: JJ Aldrich vs. Vanessa Demopoulos
Men's featherweight: Jamall Emmers vs. Pat Sabatini
Men's bantamweight: Guido Cannetti vs. Mana Martinez