Brazil's Neymar scored in a 4-1 win that leaves his former Barcelona teammate Luis Suarez and Uruguay with an uphill struggle to make the World Cup.
Raphinha turned in another eye-catching performance for Brazil on Thursday by scoring twice in the home side's 4-1 victory over Uruguay.
Chile are still reliant on old stalwarts like Arturo Vidal and Alexis Sanchez, but England-born Ben Brereton Diaz gives 'La Roja' the best chance.
Argentina beat Uruguay in World Cup qualifying thanks to goals from Lionel Messi, Rodrigo De Paul, and Lautaro Martinez.
Chile and Bolivia have the chance to get back into World Cup contention with two crucial home games over the next few days.
Brazil are leading the way in CONMEBOL qualifying, but what about the rest as this week's tripleheaders see two-thirds of games complete?
Premier League clubs which blocked South American players from traveling to World Cup qualifiers will be able to play them this weekend.
Gaston Pereiro scored in stoppage time to give Uruguay a 1-0 win over Ecuador in Thursday's World Cup qualifier in Montevideo.
The suspension of Argentina vs. Brazil took the spotlight off a competitive South American World Cup qualifying, but all eyes are back on the pitch.
South American players are in a club-vs.-country tug of war, a situation made worse by CONMEBOL's insistence on playing this year's Copa America.
Giorgian de Arrascaeta scored twice as Uruguay beat Bolivia 4-2 on Sunday to boost their chances of qualifying for the World Cup.
Brazil are comfortably out front of South America's World Cup qualifying campaign, but behind them, a lot could change between now and Qatar 2022.
Edinson Cavani's Uruguay call-up has been cancelled due to quarantine rules while Luis Suarez will miss with a knee injury.
Puma said that FIFA told them to remove two of the four stars above Uruguay's crest in time for the 2022 World Cup.
The 3-0 result flattered Argentina, but Leo Messi was once again pivotal for his nation. Colombia, meanwhile, edged past Uruguay without a No. 10.
David Ospina saved two penalties in a shootout to give Colombia victory over Uruguay and a place in the Copa America semifinals on Saturday.
Will Neymar lead Brazil to another Copa America crown, or will Lionel Messi finally win his first senior international title with Argentina?
Neymar is in form, Leo Messi is breaking records, but it's the displays of Ricardo Gareca's Peru that have been the talk of the Copa group stage.
An Edinson Cavani penalty sealed an easy 1-0 win for Uruguay against neighbours Paraguay at the Copa America.
Edinson Cavani sacrificed his position for his country again, while winning is such a habit that Brazil are in danger of taking it for granted.
An own goal in the first half and a late second from Edinson Cavani gave Uruguay a 2-0 win over Bolivia on Thursday at the Copa America.
Uruguay's Facundo Torres and Ecuador's Gonzalo Plata may be inconsistent, but they are making people sit up and take notice at the Copa America.
Chile's Arturo Vidal put through his own net to give Uruguay their first goal in five games and grant them a point in a 1-1 Copa America draw.
There were 140 known COVID-19 cases at the Copa America in Brazil on Monday, up from 66 positive tests on Thursday.
A first half goal from Guido Rodriguez, his first in 11 international appearances, gave Argentina a 1-0 win over Uruguay in a Copa America clash.