Los AngelesLakers
- 1st in Pacific Division
Los Angeles Lakers Schedule 2021-22
| DATE | OPPONENT | RESULT | W-L | Hi Points | Hi Rebounds | Hi Assists |
| Mon, 4 Oct | L123-97 | 0-1 | Monk 15 | Nunn 7 | Horton-Tucker 3 | |
| Thu, 7 Oct | L117-105 | 0-2 | Monk 18 | Davis 8 | Rondo 5 | |
| Sat, 9 Oct | L121-114 | 0-3 | Howard 23 | Howard 12 | Rondo 6 | |
| Mon, 11 Oct | L123-94 | 0-4 | Davis 19 | Jordan 5 | Davis 6 | |
| Wed, 13 Oct | L111-99 | 0-5 | Davis 20 | Westbrook 10 | Westbrook 6 | |
| Fri, 15 Oct | L116-112 | 0-6 | James 30 | Davis 12 | Reaves 7 |