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AC Milan's veteran forward Zlatan Ibrahimovic scored twice and Gianluigi Donnarumma saved a penalty as they won 4-1 at Sampdoria.
Juventus have won a ninth consecutive Serie A title following their win over Sampdoria on Sunday.
The current season has been the most difficult in Italian football history, Juventus coach Maurizio Sarri said on Saturday as he tried to explain th
Genoa moved closer to safety when they beat neighbours Sampdoria 3-1 in the Lighthouse Derby on Wednesday while Brescia were relegated.
Sampdoria's veteran forward Fabio Quagliarella inspired them to a rousing comeback at Parma on Sunday.
Federico Bonazzoli scored twice, including another acrobatic volley, to help Sampdoria to a 3-0 win over Cagliari on Wednesday.
Fabio Quagliarella scored on his return from injury and Federico Bonazzoli scored with an overhead kick to help Sampdoria beat Udinese.
Atalanta continued their remarkable season by beating Sampdoria 2-0 on Wednesday to extend their winning run to nine Serie A games.
Bologna pushed Sampdoria deeper into Serie A trouble on Sunday as they handed Claudio Ranieri's side a third 2-1 defeat in eight days.