Arizona Cardinals @ San Francisco 49ers

1-1, 1-0 Away

2-0, 1-0 Home

49ers coach Kyle Shanahan faces another disciple in game against Cardinals coach Mike LaFleur

— San Francisco 49ers coach Kyle Shanahan said he might appreciate one day how many assistants that used to work under him have become head coaches in the NFL.

Sep 25, 2026, 03:02 am - AP

Season Leaders

ARI

Passing Yards

Rushing Yards

Receiving Yards

Sacks

Tackles

Injury Report

Arizona Cardinals

Name	Status	Est. Return
Max MeltonM. MeltonCB	QuestionableToe	27 Sep
Dadrion Taylor-DemersonD. Taylor-DemersonS	QuestionableBack	27 Sep
Garrett WilliamsG. WilliamsCB	QuestionableAchilles	27 Sep
Hjalte FroholdtH. FroholdtC	QuestionableKnee	27 Sep
Roy LopezR. LopezDT	QuestionableGroin	27 Sep

San Francisco 49ers

Name	Status	Est. Return
Romello HeightR. HeightDE	QuestionableHand	27 Sep
Nick BosaN. BosaDE	QuestionableCalf	27 Sep
Mike EvansM. EvansWR	QuestionableHip	27 Sep
C.J. WestC.J. WestDT	IRUndisclosed	25 Oct
James Thompson Jr.J. Thompson Jr.DT	DoubtfulAnkle	27 Sep

Cardinals

DATE	OPP	RESULT
21/9/26	vsSEA	L31-7
14/9/26	@LAC	W26-14
29/8/26	@GB	L42-38
23/8/26	vsDAL	L34-13
14/8/26	@LV	W27-14

49ers

DATE	OPP	RESULT
21/9/26	vsMIA	W35-13
11/9/26	vsLAR	W27-7
28/8/26	@LV	W18-12
21/8/26	@LAC	W41-17
14/8/26	vsTEN	L19-13

Data is currently unavailable.

National Football Conference

NFC West	W	L	PCT	PF	PA
Seattle	2	0	1.000	44	17
San Francisco	2	0	1.000	62	20
Los Angeles	1	1	.500	35	33
Arizona	1	1	.500	33	45

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