Kansas City Chiefs Schedule 2021
| Regular Season | |||||||||
| WK | DATE | OPPONENT | RESULT | W-L | Hi Pass | Hi Rush | Hi Rec | ||
| 1 | Mon, 13 Sep | W33-29 | 1-0 | Mahomes 337 | Edwards-Helaire 43 | Hill 197 | |||
| 2 | Mon, 20 Sep | L36-35 | 1-1 | Mahomes 343 | Edwards-Helaire 46 | Kelce 109 | |||
| 3 | Sun, 26 Sep | L30-24 | 1-2 | Mahomes 260 | Edwards-Helaire 100 | Kelce 104 | |||
| 4 | Sun, 3 Oct | W42-30 | 2-2 | Mahomes 278 | Edwards-Helaire 102 | Hill 186 | |||
| 5 | Mon, 11 Oct | L38-20 | 2-3 | Mahomes 272 | Mahomes 61 | Hardman 76 | |||
| 6 | Sun, 17 Oct | W31-13 | 3-3 | Mahomes 397 | Williams 62 | Kelce 99 | |||
| 7 | Sun, 24 Oct | L27-3 | 3-4 | Mahomes 206 | Mahomes 35 | Pringle 73 | |||
| 8 | Tue, 2 Nov | W20-17 | 4-4 | Mahomes 275 | Williams 49 | Hill 94 | |||
| 9 | Mon, 8 Nov | W13-7 | 5-4 | Mahomes 166 | Williams 70 | Kelce 68 | |||
| 10 | Mon, 15 Nov | W41-14 | 6-4 | Mahomes 406 | Williams 43 | Kelce 119 | |||
| 11 | Mon, 22 Nov | W19-9 | 7-4 | Mahomes 260 | Edwards-Helaire 63 | Hill 77 | |||
| 12 | BYE WEEK | ||||||||
| 13 | Mon, 6 Dec | W22-9 | 8-4 | Mahomes 184 | Edwards-Helaire 54 | Williams 60 | |||
| WK | DATE | OPPONENT | TIME | TV | tickets | ||||
| 14 | Sun, 12 Dec | 11:30 PM | Tickets as low as $116 | ||||||
| 15 | Fri, 17 Dec | 6:50 AM | Tickets as low as $94 | ||||||
| 16 | Mon, 27 Dec | 2:55 AM | Tickets as low as $112 | ||||||
| 17 | Sun, 2 Jan | 11:30 PM | Tickets as low as $47 | ||||||
| 18 | Mon, 10 Jan | 2:55 AM | Tickets as low as $103 | ||||||
| Preseason | |||||||||
| WK | DATE | OPPONENT | RESULT | W-L | Hi Pass | Hi Rush | Hi Rec | ||
| 1 | Sun, 15 Aug | W19-16 | 1-0 | Gordon 79 | McKinnon 19 | Fountain 38 | |||
| 2 | Sat, 21 Aug | W17-10 | 2-0 | Buechele 115 | Gore 54 | Pringle 63 | |||
| 3 | Sat, 28 Aug | W28-25 | 3-0 | Buechele 231 | Gore 26 | Gore 80 | |||
